Gene

ugt1ab

ID
ZDB-GENE-040426-2762
Name
UDP glucuronosyltransferase 1 family a, b
Symbol
ugt1ab Nomenclature History
Previous Names
  • ugt1a3
  • zgc:123097
  • zgc:66393
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Enables glucuronosyltransferase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in intestinal bulb; intestine; liver; renal system; and testis. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ugt1ab Human Ortholog
No data available
Associated With ugt1ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR035595 UDP-glycosyltransferase family, conserved site
Family IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
Domain Details Per Protein
Protein Length UDP-glucuronosyl/UDP-glucosyltransferase UDP-glycosyltransferase family, conserved site
UniProtKB:D3XD50 536
UniProtKB:Q7SXE7 526
UniProtKB:Q561S7 520
UniProtKB:A8KB40 342
UniProtKB:D3XD49 290
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations