Gene

eef1da

ID

ZDB-GENE-040426-2740

Name

eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)

Symbol

eef1da Nomenclature History

Previous Names

eef1d
elongation factor-1
zgc:66406 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in translational elongation. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation elongation factor 1 complex. Predicted to be active in cytosol. Orthologous to human EEF1D (eukaryotic translation elongation factor 1 delta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:111981 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eef1da Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with thin corpus callosum, hypotonia, and absent language	621150

Associated With eef1da Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001326	Translation elongation factor EF1B, beta/delta chains, conserved site
Domain	IPR014038	Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain
Domain	IPR018940	Elongation factor 1 beta central acidic region, eukaryote
Family	IPR049720	Translation elongation factor EF1B, beta/delta subunit
Homologous_superfamily	IPR014717	Translation elongation factor EF1B/small ribosomal subunit protein bS6
Homologous_superfamily	IPR036219	Translation elongation factor eEF-1beta-like superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M6Z1P2	InterPro	463
UniProtKB:A0A8M9QAS6	InterPro	441
UniProtKB:A0A8M9QP05	InterPro	439
UniProtKB:A0A8M2BAS2	InterPro	291
UniProtKB:A0A8M2BAP5	InterPro	267
UniProtKB:A0A0R4IA30	InterPro	245
UniProtKB:A0A8M9QG85	InterPro	417
UniProtKB:A0A8M2BAX4	InterPro	269
UniProtKB:A0AB32TYT4	InterPro	439

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	eef1da-201 (1) Ensembl	Ensembl	935 nt	Select Tool ZFIN BLAST
mRNA	eef1da-202 (1) Ensembl	Ensembl	492 nt	Select Tool ZFIN BLAST
mRNA	eef1da-203 (1) Ensembl	Ensembl	458 nt	Select Tool ZFIN BLAST
mRNA	eef1da-204 (1) Ensembl	Ensembl	813 nt	Select Tool ZFIN BLAST
mRNA	eef1da-205 (1) Ensembl	Ensembl	845 nt	Select Tool ZFIN BLAST
mRNA	eef1da-207 (1) Ensembl	Ensembl	806 nt	Select Tool ZFIN BLAST
mRNA	eef1da-208 (1) Ensembl	Ensembl	767 nt	Select Tool ZFIN BLAST
mRNA	eef1da-209 (1) Ensembl	Ensembl	5,140 nt	Select Tool ZFIN BLAST
ncRNA	eef1da-006 (1) Ensembl	Ensembl	745 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations