Gene
hnrnpdl
- ID
- ZDB-GENE-040426-2717
- Name
- heterogeneous nuclear ribonucleoprotein D-like
- Symbol
- hnrnpdl Nomenclature History
- Previous Names
-
- hnrpdl
- wu:fa11d08
- zgc:66169 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity. Predicted to be involved in regulation of gene expression. Predicted to be located in cytoplasm. Predicted to be part of ribonucleoprotein complex. Predicted to be active in chromatin and nucleoplasm. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 3. Orthologous to human HNRNPDL (heterogeneous nuclear ribonucleoprotein D like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66169 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Vieira et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant limb-girdle muscular dystrophy type 3 | Alliance | Muscular dystrophy, limb-girdle, autosomal dominant 3 | 609115 |
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Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain |
|---|---|---|---|---|---|
| UniProtKB:Q7SXN2 | InterPro | 296 | |||
| UniProtKB:A0A8M9QKN0 | InterPro | 295 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hnrnpdl-201
(1)
|
Ensembl | 1,449 nt | ||
| mRNA |
hnrnpdl-205
(1)
|
Ensembl | 789 nt | ||
| mRNA |
hnrnpdl-206
(1)
|
Ensembl | 1,343 nt | ||
| ncRNA |
hnrpdl-003
(1)
|
Ensembl | 428 nt | ||
| ncRNA |
hnrpdl-004
(1)
|
Ensembl | 537 nt |
1 - 5 of 6 Show all
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-249H16 | ZFIN Curated Data | |
| Encodes | EST | fa11d08 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:66169 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001328494 (1) | 1358 nt | ||
| Genomic | GenBank:BX936392 (1) | 180785 nt | ||
| Polypeptide | UniProtKB:Q7SXN2 (1) | 296 aa |
- Fouchécourt, S., Picolo, F., Elis, S., Lécureuil, C., Thélie, A., Govoroun, M., Brégeon, M., Papillier, P., Lareyre, J.J., Monget, P. (2019) An evolutionary approach to recover genes predominantly expressed in the testes of the zebrafish, chicken and mouse. BMC Evolutionary Biology. 19:137
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Du, Z., Chen, X., Li, X., He, K., Ji, S., Shi, W., Hao, A. (2016) Protein palmitoylation activate zygotic gene expression during the maternal-to-zygotic transition. Biochemical and Biophysical Research Communications. 475(2):194-201
- Vieira, N.M., Naslavsky, M.S., Licinio, L., Kok, F., Schlesinger, D., Vainzof, M., Sanchez, N., Kitajima, J.P., Gal, L., Cavaçana, N., Serafini, P.R., Chuartzman, S., Vasquez, C., Mimbacas, A., Nigro, V., Pavanello, R.C., Schuldiner, M., Kunkel, L.M., Zatz, M. (2014) A defect in the RNA-processing protein HNRPDL causes limb-girdle muscular dystrophy 1G (LGMD1G). Human molecular genetics. 23(15):4103-10
- Huang, Q.Y., Huang, L., and Huang, H.Q. (2011) Proteomic analysis of methyl parathion-responsive proteins in zebrafish (Danio rerio) brain. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 153(1):67-74
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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