Gene

klhl21

ID

ZDB-GENE-040426-2627

Name

kelch-like family member 21

Symbol

klhl21 Nomenclature History

Previous Names

zgc:76933

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including COPII vesicle coating; chromosome passenger complex localization to spindle midzone; and protein monoubiquitination. Predicted to localize to COPII-coated ER to Golgi transport vesicle; Cul3-RING ubiquitin ligase complex; and polar microtubule. Orthologous to human KLHL21 (kelch like family member 21).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With klhl21 Human Ortholog

No data available

Associated With klhl21 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000210	BTB/POZ domain
Domain	IPR011705	BTB/Kelch-associated
Domain	IPR030577	Kelch-like protein 21, BTB/POZ domain
Domain	IPR047069	Kelch-like protein 21, BACK domain
Family	IPR017096	BTB-kelch protein
Homologous_superfamily	IPR011333	SKP1/BTB/POZ domain superfamily
Homologous_superfamily	IPR015915	Kelch-type beta propeller
Repeat	IPR006652	Kelch repeat type 1

Domain Details Per Protein

Protein	Length	BTB/Kelch-associated	BTB-kelch protein	BTB/POZ domain	Kelch-like protein 21, BACK domain	Kelch-like protein 21, BTB/POZ domain	Kelch repeat type 1	Kelch-type beta propeller	SKP1/BTB/POZ domain superfamily
UniProtKB:Q6NYM1 InterPro	613
UniProtKB:A0A8M9P526 InterPro	613

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	klhl21-201 (1) Ensembl	Havana	523 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	klhl21-202 (1) Ensembl	Havana	3896 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	klhl21-203 (1) Ensembl	Havana	3902 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations