Gene

ehd1a

ID

ZDB-GENE-040426-2518

Name

EH-domain containing 1a

Symbol

ehd1a Nomenclature History

Previous Names

zgc:77049

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to enable ATP binding activity; GTP binding activity; and calcium ion binding activity. Involved in cilium assembly. Acts upstream of or within renal absorption. Predicted to be located in endosome and membrane. Predicted to be active in cytoplasmic vesicle; perinuclear region of cytoplasm; and plasma membrane. Is expressed in several structures, including heart; liver; nervous system; otic vesicle; and pleuroperitoneal region. Orthologous to human EHD1 (EH domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ehd1a Human Ortholog

No data available

Associated With ehd1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR000261	EH domain
Domain	IPR002048	EF-hand domain
Domain	IPR030381	Dynamin-type guanine nucleotide-binding (G) domain
Domain	IPR031692	EH domain-containing protein, N-terminal
Domain	IPR040990	Domain of unknown function DUF5600
Domain	IPR045063	Dynamin, N-terminal
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase