Gene
ethe1
- ID
- ZDB-GENE-040426-2503
- Name
- ETHE1 persulfide dioxygenase
- Symbol
- ethe1 Nomenclature History
- Previous Names
-
- zgc:85680
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have hydrolase activity, acting on ester bonds and sulfur dioxygenase activity. Predicted to be involved in glutathione metabolic process and hydrogen sulfide metabolic process. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in ethylmalonic encephalopathy. Orthologous to human ETHE1 (ETHE1 persulfide dioxygenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85680 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ethylmalonic encephalopathy | Alliance | Ethylmalonic encephalopathy | 602473 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Metallo-beta-lactamase | Mitochondrial Persulfide Dioxygenase | Persulfide dioxygenase-like, MBL-fold metallo-hydrolase domain | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
|---|---|---|---|---|---|
|
UniProtKB:Q6NWI8
|
279 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available