Gene
wfikkn1
- ID
- ZDB-GENE-040426-2465
- Name
- WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
- Symbol
- wfikkn1 Nomenclature History
- Previous Names
-
- Gasp2 (1)
- zgc:85816
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable receptor antagonist activity and transforming growth factor beta binding activity. Predicted to be involved in transforming growth factor beta receptor signaling pathway. Predicted to act upstream of or within negative regulation of peptidase activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85816 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Shankar et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020901 | Proteinase inhibitor I2, Kunitz, conserved site |
| Domain | IPR001134 | Netrin domain |
| Domain | IPR002223 | Pancreatic trypsin inhibitor Kunitz domain |
| Domain | IPR002350 | Kazal domain |
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR008197 | WAP-type 'four-disulfide core' domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR018933 | Netrin module, non-TIMP type |
| Homologous_superfamily | IPR008993 | Tissue inhibitor of metalloproteinases-like, OB-fold |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036058 | Kazal domain superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
| Homologous_superfamily | IPR036645 | Elafin-like superfamily |
| Homologous_superfamily | IPR036880 | Pancreatic trypsin inhibitor Kunitz domain superfamily |
Domain Details Per Protein
| Protein | Length | Elafin-like superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Kazal domain | Kazal domain superfamily | Netrin domain | Netrin module, non-TIMP type | Pancreatic trypsin inhibitor Kunitz domain | Pancreatic trypsin inhibitor Kunitz domain superfamily | Proteinase inhibitor I2, Kunitz, conserved site | Tissue inhibitor of metalloproteinases-like, OB-fold | WAP-type 'four-disulfide core' domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NUX0
|
558 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
wfikkn1-201
(1)
|
Ensembl | 2,270 nt | ||
| mRNA |
wfikkn1-202
(1)
|
Ensembl | 1,335 nt |
Interactions and Pathways
No data available
Plasmids
No data available