Gene
tmem107
- ID
- ZDB-GENE-040426-2294
- Name
- transmembrane protein 107
- Symbol
- tmem107 Nomenclature History
- Previous Names
-
- zgc:77926 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to be involved in non-motile cilium assembly and protein localization to ciliary transition zone. Predicted to localize to MKS complex. Human ortholog(s) of this gene implicated in Meckel syndrome 13 and orofaciodigital syndrome XVI. Orthologous to human TMEM107 (transmembrane protein 107).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77926 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Meckel syndrome 13 | Alliance | Meckel syndrome 13 | 617562 |
| Meckel syndrome 13 | Alliance | ?Joubert syndrome 29 | 617562 |
| orofaciodigital syndrome XVI | Alliance | Orofaciodigital syndrome XVI | 617563 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR029248 | Transmembrane protein 107 |
Domain Details Per Protein
| Protein | Length | Transmembrane protein 107 |
|---|---|---|
|
UniProtKB:Q6NZZ4
|
135 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmem107-201
(1)
|
Ensembl | 1,450 nt |
Interactions and Pathways
No data available
Plasmids
No data available