Gene
pla2g7
- ID
- ZDB-GENE-040426-2248
- Name
- phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
- Symbol
- pla2g7 Nomenclature History
- Previous Names
-
- zgc:77563 (1)
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable 1-alkyl-2-acetylglycerophosphocholine esterase activity. Predicted to act upstream of or within lipid catabolic process. Is expressed in lens and solid lens vesicle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); glomerulonephritis (multiple); hemolytic-uremic syndrome; proteinuria (multiple); and type 2 diabetes mellitus. Orthologous to human PLA2G7 (phospholipase A2 group VII).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77563 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Platelet-activating factor acetylhydrolase deficiency | 614278 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Platelet-activating factor acetylhydrolase-like, eukaryote |
|---|---|---|---|
|
UniProtKB:Q6NYI7
|
404 | ||
|
UniProtKB:Q5RHM0
|
444 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pla2g7-201
(1)
|
Ensembl | 2,602 nt | ||
| mRNA |
pla2g7-202
(1)
|
Ensembl | 721 nt | ||
| ncRNA |
pla2g7-002
(1)
|
Ensembl | 493 nt |
Interactions and Pathways
No data available
Plasmids
No data available