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ZIRC
ZFIN ID: ZDB-GENE-040426-2101
Gene Name: TEA domain family member 1a
Gene Symbol: tead1a    Nomenclature History

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Previous Names: tead1, zgc:63696

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have DNA binding activity; DNA-binding transcription factor activity; and RNA polymerase II transcription factor binding activity. Predicted to be involved in hippo signaling and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus and transcription factor complex. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Is expressed in nervous system; neural plate; and somite. Orthologous to human TEAD1 (TEA domain transcription factor 1).
Genome Resources: Alliance (1),  Gene:405773 (1),  Ensembl(GRCz11):ENSDARG00000028159 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014669Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023162Tg Transgenic Insertion Unknown Unknown DNA
    sa44258 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-tead1a
    1
    CRISPR2-tead1a
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tead1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Sveinsson chorioretinal atrophy Alliance Sveinsson chorioretinal atrophy 108985
    DISEASE ASSOCIATED WITH tead1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hippo signaling (more)
    Cellular Component nucleus (more)
    Molecular Function protein binding (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tead1a-201 (1)    Ensembl 748
    tead1a-202 (1)    Ensembl 1744
    ncRNA tead1a-003 (1)    Ensembl 817
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tead1a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(14xUAS:DsRed,MYC-tead1a_Y417H) UAS DsRedMYCtead1a Danio rerio 1 1
    MARKER RELATIONSHIPS
    tead1a Contained in: [BAC] CH211-166I5 (1) (order this), CH211-254K13 (1) (order this)
    tead1a Encodes: [cDNA] MGC:63696 (1) (order this), MGC:113979 (1) (order this), MGC:174255 (1) (order this), MGC:191697 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212847 (1) 1684 bp
    Genomic GenBank:BX908400 (1) 136937 bp
    Select Tool
    Polypeptide UniProtKB:F1QLL3 (1) 422 aa
    Sequence Clusters UniGene:87037 (1)
    Sequence Information (all 30)
    ORTHOLOGY for tead1a ( Chr: 25 )
    CITATIONS (27)