pak5

ID

ZDB-GENE-040426-2085

Name

p21 protein (Cdc42/Rac)-activated kinase 5

Symbol

pak5 Nomenclature History

Previous Names

pak5 (1)
pak6 (1)
pak7
zgc:76890

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in apoptotic process and cytoskeleton organization. Is expressed in central nervous system and spinal cord. Orthologous to human PAK5 (p21 (RAC1) activated kinase 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:76890 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pak5 Human Ortholog

No data available

Associated With pak5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000095	CRIB domain
Domain	IPR000719	Protein kinase domain
Domain	IPR028754	Serine/threonine-protein kinase PAK5, catalytic domain
Domain	IPR033923	p21 activated kinase binding domain
Family	IPR051931	Serine/threonine-protein kinase PAK 3-like
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR036936	CRIB domain superfamily