ampd1

ID

ZDB-GENE-040426-1906

Name

adenosine monophosphate deaminase 1 (isoform M)

Symbol

ampd1 Nomenclature History

Previous Names

zgc:77905

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable AMP deaminase activity. Predicted to be involved in AMP metabolic process and IMP biosynthetic process. Predicted to be active in cytosol. Is expressed in cephalic musculature; myotome; pectoral fin musculature; and trunk musculature. Human ortholog(s) of this gene implicated in congestive heart failure; coronary artery disease; and left ventricular failure. Orthologous to human AMPD1 (adenosine monophosphate deaminase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:77905 (8 images)
IMAGE:6908427 (4 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ampd1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Myopathy due to myoadenylate deaminase deficiency	615511

Associated With ampd1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR006650	Adenosine/AMP deaminase active site
Family	IPR006329	AMP deaminase
Homologous_superfamily	IPR032466	Metal-dependent hydrolase

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M6Z0E5	InterPro	723
UniProtKB:A0A8M6YZQ5	InterPro	718
UniProtKB:A0A8M6Z814	InterPro	719
UniProtKB:Q6P3G5	InterPro	717
UniProtKB:A0A8M6Z216	InterPro	722