ZFIN is now using GRCz12tu for Genomic Data
Gene
naprt
- ID
- ZDB-GENE-040426-1897
- Name
- nicotinate phosphoribosyltransferase
- Symbol
- naprt Nomenclature History
- Previous Names
-
- naprt1
- zgc:77870
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable nicotinate phosphoribosyltransferase activity. Predicted to be involved in NAD+ biosynthetic process via the salvage pathway and response to oxidative stress. Predicted to be active in cytosol. Is expressed in several structures, including alar plate midbrain region; digestive system; midbrain; polster; and pronephric duct. Orthologous to human NAPRT (nicotinate phosphoribosyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77870 (14 images)
- IMAGE:7160001 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR040727 | Nicotinate phosphoribosyltransferase, N-terminal domain |
Domain | IPR041619 | Nicotinate phosphoribosyltransferase C-terminal domain |
Family | IPR006405 | Nicotinate phosphoribosyltransferase pncB-type |
Family | IPR007229 | Nicotinate phosphoribosyltransferase family |
Homologous_superfamily | IPR013785 | Aldolase-type TIM barrel |
Homologous_superfamily | IPR036068 | Nicotinate phosphoribosyltransferase-like, C-terminal |
Domain Details Per Protein
Protein | Additional Resources | Length | Aldolase-type TIM barrel | Nicotinate phosphoribosyltransferase C-terminal domain | Nicotinate phosphoribosyltransferase family | Nicotinate phosphoribosyltransferase-like, C-terminal | Nicotinate phosphoribosyltransferase, N-terminal domain | Nicotinate phosphoribosyltransferase pncB-type |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M2BHL0 | InterPro | 547 | ||||||
UniProtKB:Q6P3H4 | InterPro | 546 | ||||||
UniProtKB:B8JLT0 | InterPro | 548 |
Interactions and Pathways
No data available
Plasmids
No data available