Gene
stx11b.1
- ID
- ZDB-GENE-040426-1893
- Name
- syntaxin 11b, tandem duplicate 1
- Symbol
- stx11b.1 Nomenclature History
- Previous Names
-
- zgc:77855
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport; synaptic vesicle fusion to presynaptic active zone membrane; and vesicle docking. Predicted to act upstream of or within vesicle-mediated transport. Predicted to be part of SNARE complex. Predicted to be active in presynaptic active zone membrane and synaptic vesicle. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 4. Orthologous to human STX11 (syntaxin 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial hemophagocytic lymphohistiocytosis 4 | Alliance | Hemophagocytic lymphohistiocytosis, familial, 4 | 603552 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | SNARE | Syntaxin | Syntaxin, N-terminal domain | Target SNARE coiled-coil homology domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6P5J5
|
295 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stx11b.1-201
(1)
|
Ensembl | 1,556 nt |
Interactions and Pathways
No data available
Plasmids
No data available