Gene

plpp7a

ID

ZDB-GENE-040426-1822

Name

phospholipid phosphatase 7a (inactive)

Symbol

plpp7a Nomenclature History

Previous Names

plpp7
im:7142624
ppapdc3
zgc:77336

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable sphingosine-1-phosphate phosphatase activity. Predicted to be located in endoplasmic reticulum membrane and nucleus. Predicted to be active in membrane and nuclear envelope. Is expressed in nervous system; optic vesicle; pancreatic system; and pharyngeal arch. Orthologous to human PLPP7 (phospholipid phosphatase 7 (inactive)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:77336 (23 images)
IMAGE:7142624 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

No data available

Sequence Targeting Reagents

No data available

Human Disease

Associated With plpp7a Human Ortholog

No data available

Associated With plpp7a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000326	Phosphatidic acid phosphatase type 2/haloperoxidase
Homologous_superfamily	IPR036938	Phosphatidic acid phosphatase type 2/haloperoxidase superfamily

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Domain Details Per Protein

Protein	Length	Phosphatidic acid phosphatase type 2/haloperoxidase	Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
UniProtKB:Q6P0E8 InterPro	287

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Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 5

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	plpp7-201 (1) Ensembl	Ensembl		2,709 nt	Select Tool ZFIN BLAST

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Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	CH211-95J7	CU856179	ZFIN Curated Data
Contained in	BAC	CH211-147G21	AL929057	ZFIN Curated Data
Encodes	EST	IMAGE:7142624	CK680869	Thisse et al., 2004
Encodes	cDNA	MGC:77336	BC065648	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_205660 (1)	2750 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX950178 (1)	175858 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q6P0E8 (1)	287 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	PLPP7	9	Ensembl:ENSG00000160539 Gene:84814 OMIM:618743 HGNC:28174	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)
Mouse	Plpp7	2	Ensembl:ENSMUSG00000051373 MGI:2445183 Gene:227721	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

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