ZFIN is now using GRCz12tu for Genomic Data
Gene
hmox1b
- ID
- ZDB-GENE-040426-1807
- Name
- heme oxygenase 1b
- Symbol
- hmox1b Nomenclature History
- Previous Names
-
- zgc:77234 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable heme binding activity and heme oxygenase (decyclizing) activity. Predicted to be involved in heme catabolic process; heme oxidation; and response to oxidative stress. Predicted to be located in endoplasmic reticulum. Is expressed in several structures, including digestive system; gill; solid lens vesicle; vein; and visual system. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); factor VIII deficiency; heart disease (multiple); and lung disease (multiple). Orthologous to human HMOX1 (heme oxygenase 1).
- Genome Resources
-
- Alliance (1)
- Gene:402970 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77234 (3 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| chronic obstructive pulmonary disease | Alliance | {Pulmonary disease, chronic obstructive, susceptibility to} | 606963 |
| Heme oxygenase-1 deficiency | 614034 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Haem oxygenase | Haem oxygenase conserved site | Haem oxygenase-like | Haem oxygenase-like, multi-helical |
|---|---|---|---|---|---|---|
| UniProtKB:A0AC58JQV5 | InterPro | 277 | ||||
| UniProtKB:A0AC58JQZ0 | InterPro | 247 | ||||
| UniProtKB:A0AC36K568 | InterPro | 247 |
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance