ZFIN is now using GRCz12tu for Genomic Data
Gene
txn2
- ID
- ZDB-GENE-040426-1795
- Name
- thioredoxin 2
- Symbol
- txn2 Nomenclature History
- Previous Names
-
- zgc:77127
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein-disulfide reductase activity. Predicted to be involved in cell redox homeostasis. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 29. Orthologous to human TXN2 (thioredoxin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77127 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined oxidative phosphorylation deficiency 29 | Alliance | ?Combined oxidative phosphorylation deficiency 29 | 616811 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Thioredoxin | Thioredoxin, conserved site | Thioredoxin domain | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q6P131 | InterPro | 166 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers