Gene

dtx3

ID

ZDB-GENE-040426-1640

Name

deltex E3 ubiquitin ligase 3

Symbol

dtx3 Nomenclature History

Previous Names

fi25g12
wu:fi25g12
zgc:66440

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have ubiquitin protein ligase activity. Predicted to be involved in Notch signaling pathway and protein ubiquitination. Predicted to localize to nucleoplasm. Orthologous to human DTX3 (deltex E3 ubiquitin ligase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66440 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dtx3 Human Ortholog

No data available

Associated With dtx3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017907	Zinc finger, RING-type, conserved site
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR039396	Deltex, C-terminal
Family	IPR039398	Deltex family
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR039399	Deltex, C-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Deltex, C-terminal	Deltex, C-terminal domain superfamily	Deltex family	Zinc finger, RING/FYVE/PHD-type	Zinc finger, RING-type	Zinc finger, RING-type, conserved site
UniProtKB:Q4G0B5 InterPro	290
UniProtKB:A0A8M2B9F2 InterPro	369
UniProtKB:A0A8M3B638 InterPro	360
UniProtKB:F1QUJ1 InterPro	384

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	dtx3-206 (1) Ensembl	Ensembl	1,116 nt	Select Tool ZFIN BLAST
mRNA	zgc:66440-201 (1) Ensembl	Ensembl	2,585 nt	Select Tool
mRNA	zgc:66440-202 (1) Ensembl	Ensembl	2,449 nt	Select Tool
mRNA	zgc:66440-203 (1) Ensembl	Ensembl	566 nt	Select Tool
mRNA	zgc:66440-204 (1) Ensembl	Ensembl	807 nt	Select Tool
mRNA	zgc:66440-205 (1) Ensembl	Ensembl	614 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations