Gene
rnf180b
- ID
- ZDB-GENE-040426-1620
- Name
- ring finger protein 180b
- Symbol
- rnf180b Nomenclature History
- Previous Names
-
- rnf180
- zgc:66368 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in norepinephrine metabolic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and serotonin metabolic process. Predicted to act upstream of or within protein polyubiquitination. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human RNF180 (ring finger protein 180).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66368 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR045790 | E3 ubiquitin-protein ligase RNF180, C-terminal domain |
| Family | IPR033263 | E3 ubiquitin-protein ligase RNF180 |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Length | E3 ubiquitin-protein ligase RNF180 | E3 ubiquitin-protein ligase RNF180, C-terminal domain | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|---|
|
UniProtKB:A8WGN5
|
458 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rnf180-001
(1)
|
Ensembl | 1,987 nt | ||
| ncRNA |
rnf180-002
(1)
|
Ensembl | 875 nt |
Interactions and Pathways
No data available
Plasmids
No data available