Gene
klc1a
- ID
- ZDB-GENE-040426-1599
- Name
- kinesin light chain 1a
- Symbol
- klc1a Nomenclature History
- Previous Names
-
- zgc:66299 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable kinesin binding activity. Acts upstream of or within anterior commissure morphogenesis and posterior commissure morphogenesis. Predicted to be located in microtubule. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm. Is expressed in central nervous system; cranial ganglion; neurons; retina; and retinal ganglion cell layer. Human ortholog(s) of this gene implicated in Alzheimer's disease and relapsing-remitting multiple sclerosis. Orthologous to human KLC1 (kinesin light chain 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66299 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Li et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Kinesin light chain | Kinesin light chain repeat | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B3J0 | InterPro | 647 | ||||
| UniProtKB:A0A8M2B2P5 | InterPro | 557 | ||||
| UniProtKB:A0A8M2B2S3 | InterPro | 548 | ||||
| UniProtKB:F1QS14 | InterPro | 605 | ||||
| UniProtKB:Q7SXI2 | InterPro | 538 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available