Gene

stx3b

ID

ZDB-GENE-040426-1489

Name

syntaxin 3b

Symbol

stx3b Nomenclature History

Previous Names

stx3a
zgc:65954 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport; synaptic vesicle fusion to presynaptic active zone membrane; and vesicle docking. Predicted to localize to several cellular components, including SNARE complex; presynaptic active zone membrane; and synaptic vesicle. Is expressed in anterior axial hypoblast; hatching gland; notochord; polster; and retina. Orthologous to human STX3 (syntaxin 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:65954 (4 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With stx3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Diarrhea 12, with microvillus atrophy	619445
		Retinal dystrophy and microvillus inclusion disease	619446

Associated With stx3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR006012	Syntaxin/epimorphin, conserved site
Domain	IPR000727	Target SNARE coiled-coil homology domain
Domain	IPR006011	Syntaxin, N-terminal domain
Domain	IPR031186	Syntaxin-3, SNARE motif
Family	IPR045242	Syntaxin
Homologous_superfamily	IPR010989	SNARE

Domain Details Per Protein

Protein	Length	SNARE	Syntaxin	Syntaxin-3, SNARE motif	Syntaxin/epimorphin, conserved site	Syntaxin, N-terminal domain	Target SNARE coiled-coil homology domain
UniProtKB:A0A8M9QAZ2 InterPro	248
UniProtKB:A0A8M9QP33 InterPro	285
UniProtKB:Q6PHV0 InterPro	288
UniProtKB:A0A8M2BKE2 InterPro	343
UniProtKB:A0A8M9QKI8 InterPro	285
UniProtKB:A0A8M2BKT9 InterPro	285
UniProtKB:A0A8M9PZ48 InterPro	255

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	stx3b-201 (1) Ensembl	Ensembl	2,051 nt	Select Tool
mRNA	stx3b-203 (1) Ensembl	Ensembl	1,275 nt	Select Tool
mRNA	stx3-204 (1) Ensembl	Ensembl	864 nt	Select Tool ZFIN BLAST
ncRNA	stx3b-202 (1) Ensembl	Ensembl	227 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations