Gene
fzd6
- ID
- ZDB-GENE-040426-1451
- Name
- frizzled class receptor 6
- Symbol
- fzd6 Nomenclature History
- Previous Names
-
- zgc:65879
- zgc:77440
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have Wnt-activated receptor activity. Involved in angiogenesis and embryonic cranial skeleton morphogenesis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 1. Is expressed in head; nervous system; and pectoral fin. Orthologous to human FZD6 (frizzled class receptor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77440 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nonsyndromic congenital nail disorder 1 | Alliance | Nail disorder, nonsyndromic congenital, 1 | 161050 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000539 | Frizzled/Smoothened, 7TM |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Domain | IPR020067 | Frizzled domain |
| Domain | IPR041770 | Frizzled 6, cysteine-rich domain |
| Family | IPR015526 | Frizzled/secreted frizzled-related protein |
| Homologous_superfamily | IPR036790 | Frizzled cysteine-rich domain superfamily |
Domain Details Per Protein
| Protein | Length | Frizzled 6, cysteine-rich domain | Frizzled cysteine-rich domain superfamily | Frizzled domain | Frizzled/secreted frizzled-related protein | Frizzled/Smoothened, 7TM | GPCR, family 2-like, 7TM |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6P0Y7
|
617 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available