Gene

slc18a3b

ID
ZDB-GENE-040426-1410
Name
solute carrier family 18 member 3b
Symbol
slc18a3b Nomenclature History
Previous Names
  • vchat (1)
  • zSlc18a3 (1)
  • vachtb (1)
  • vesicular acetylcholine transporter b (1)
  • zgc:64220
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have acetylcholine transmembrane transporter activity. Predicted to be involved in chemical synaptic transmission. Predicted to localize to AP-1 adaptor complex; AP-2 adaptor complex; and terminal bouton. Is expressed in central nervous system. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 21. Orthologous to human SLC18A3 (solute carrier family 18 member A3).
Genome Resources
Note
None
Expression
All Expression Data
13 figures from 7 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc18a3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital myasthenic syndrome 21 Alliance Myasthenic syndrome, congenital, 21, presynaptic 617239
Associated With slc18a3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR020846 Major facilitator superfamily domain
Family IPR004734 Multidrug resistance protein
Family IPR011701 Major facilitator superfamily
Homologous_superfamily IPR036259 MFS transporter superfamily
Domain Details Per Protein
Protein Length Major facilitator superfamily Major facilitator superfamily domain MFS transporter superfamily Multidrug resistance protein
UniProtKB:P59845 493
UniProtKB:A0A2R8QBK8 431
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations