Gene

tle5

ID

ZDB-GENE-040426-1409

Name

TLE family member 5, transcriptional modulator

Symbol

tle5 Nomenclature History

Previous Names

aes
zgc:64216

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have repressing transcription factor binding activity and transcription corepressor activity. Involved in dorsal/ventral axis specification. Predicted to localize to nucleus and transcription factor complex. Orthologous to human TLE5 (TLE family member 5, transcriptional modulator).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tle5 Human Ortholog

No data available

Associated With tle5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR005617	Groucho/TLE, N-terminal Q-rich domain
Family	IPR009146	Groucho/transducin-like enhancer

Domain Details Per Protein

Protein	Length	Groucho/TLE, N-terminal Q-rich domain	Groucho/transducin-like enhancer
UniProtKB:Q7T289 InterPro	197
UniProtKB:A0A8M2BI66 InterPro	196

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	aes-201 (1) Ensembl	Ensembl		1,692 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations