Gene

cacng2a

ID
ZDB-GENE-040426-1401
Name
calcium channel, voltage-dependent, gamma subunit 2a
Symbol
cacng2a Nomenclature History
Previous Names
  • cacng2
  • zgc:64200 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have voltage-gated calcium channel activity. Involved in AMPA selective glutamate receptor signaling pathway. Predicted to localize to AMPA glutamate receptor complex and postsynaptic density membrane. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 10. Is expressed in brain and central nervous system. Orthologous to human CACNG2 (calcium voltage-gated channel auxiliary subunit gamma 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Roy et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cacng2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant intellectual developmental disorder 10 Alliance ?Intellectual developmental disorder, autosomal dominant 10 614256
Associated With cacng2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004031 PMP-22/EMP/MP20/Claudin superfamily
Family IPR005422 Voltage-dependent calcium channel, gamma-2 subunit
Family IPR008368 Voltage-dependent calcium channel, gamma subunit
Domain Details Per Protein
Protein Length PMP-22/EMP/MP20/Claudin superfamily Voltage-dependent calcium channel, gamma-2 subunit Voltage-dependent calcium channel, gamma subunit
UniProtKB:Q6PFS3 324
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations