Gene
prkcba
- ID
- ZDB-GENE-040426-1354
- Name
- protein kinase C, beta a
- Symbol
- prkcba Nomenclature History
- Previous Names
-
- prkcb1l
- zgc:64063 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and lung non-small cell carcinoma. Is expressed in several structures, including brain; forebrain neural keel; otic placode; pectoral fin musculature; and pronephros. Orthologous to human PRKCB (protein kinase C beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64063 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000008 | C2 domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR017892 | Protein kinase, C-terminal |
| Domain | IPR020454 | Diacylglycerol/phorbol-ester binding |
| Family | IPR014375 | Protein kinase C, alpha/beta/gamma types |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AGC-kinase, C-terminal | C1-like domain superfamily | C2 domain | C2 domain superfamily | Diacylglycerol/phorbol-ester binding | Protein kinase, ATP binding site | Protein kinase C, alpha/beta/gamma types | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Protein kinase, C-terminal | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7T2C5
|
668 | ||||||||||||
|
UniProtKB:A0A8M2BI27
|
667 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prkcba-201
(1)
|
Ensembl | 2,481 nt | ||
| mRNA |
prkcba-202
(1)
|
Ensembl | 1,155 nt |
Interactions and Pathways
No data available
Plasmids
No data available