Gene
rab7a
- ID
- ZDB-GENE-040426-1352
- Name
- RAB7a, member RAS oncogene family
- Symbol
- rab7a Nomenclature History
- Previous Names
-
- rab7 (1)
- zgc:64058
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity and GTPase activity. Acts upstream of or within endosomal transport. Located in late endosome. Is expressed in eye; neural crest; and telencephalon. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B. Orthologous to human RAB7A (RAB7A, member RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7150470 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease type 2B | Alliance | Charcot-Marie-Tooth disease, type 2B | 600882 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|
|
UniProtKB:Q7T2C6
|
207 |
Interactions and Pathways
No data available
Plasmids