Gene

ptger2a

ID
ZDB-GENE-040426-1321
Name
prostaglandin E receptor 2a (subtype EP2)
Symbol
ptger2a Nomenclature History
Previous Names
  • ep2 (1)
  • PRS2 (1)
  • ptger2l
  • zgc:63974
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Exhibits prostaglandin E receptor activity. Involved in embryonic liver development and exocrine pancreas development. Predicted to localize to plasma membrane. Is expressed in several structures, including endoderm; hematopoietic stem cell; intermediate mesoderm; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance. Orthologous to human PTGER2 (prostaglandin E receptor 2).
Genome Resources
Note
None
Expression
All Expression Data
9 figures from 9 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptger2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
asthma, nasal polyps, and aspirin intolerance Alliance {Asthma, aspirin-induced, susceptibility to} 208550
Associated With ptger2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000370 Prostacyclin (prostanoid IP) receptor
Family IPR001923 Prostanoid EP2 receptor
Family IPR008365 Prostanoid receptor
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Prostacyclin (prostanoid IP) receptor Prostanoid EP2 receptor Prostanoid receptor
UniProtKB:Q2MV23 368
UniProtKB:Q6PFT8 281
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations