Gene
slc33a1
- ID
- ZDB-GENE-040426-1241
- Name
- solute carrier family 33 member 1
- Symbol
- slc33a1 Nomenclature History
- Previous Names
-
- zgc:63693
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have solute:proton symporter activity. Involved in central nervous system neuron axonogenesis and negative regulation of BMP signaling pathway. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 42. Orthologous to human SLC33A1 (solute carrier family 33 member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63693 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 42 | Alliance | Spastic paraplegia 42, autosomal dominant | 612539 |
| Huppke-Brendel syndrome | 614482 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Acetyl-coenzyme A transporter 1-like | AmpG-like permease/Acetyl-coenzyme A transporter 1 | MFS transporter superfamily |
|---|---|---|---|---|
|
UniProtKB:Q7SXX6
|
543 | |||
|
UniProtKB:B8JLW5
|
541 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc33a1-201
(1)
|
Ensembl | 1,834 nt | ||
| mRNA |
slc33a1-202
(1)
|
Ensembl | 2,234 nt |
Interactions and Pathways
No data available
Plasmids
No data available