Gene

cdc14aa

ID
ZDB-GENE-040426-1214
Name
cell division cycle 14Aa
Symbol
cdc14aa Nomenclature History
Previous Names
  • cdc14a1 (1)
  • zgc:63654 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Acts upstream of or within cilium assembly. Located in centrosome and spindle pole. Is expressed in Kupffer's vesicle; forerunner cell group; nervous system; neural tube; and pronephric duct. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 32. Orthologous to human CDC14A (cell division cycle 14A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdc14aa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 32 Alliance Deafness, autosomal recessive 32, with or without immotile sperm 608653
Associated With cdc14aa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR016130 Protein-tyrosine phosphatase, active site
Domain IPR000387 Tyrosine specific protein phosphatases domain
Domain IPR020422 Dual specificity protein phosphatase domain
Domain IPR029260 Dual specificity/tyrosine protein phosphatase, N-terminal
Family IPR026068 Dual specificity protein phosphatase CDC14A
Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
Domain Details Per Protein
Protein Length Dual specificity protein phosphatase CDC14A Dual specificity protein phosphatase domain Dual specificity/tyrosine protein phosphatase, N-terminal Protein-tyrosine phosphatase, active site Protein-tyrosine phosphatase-like Tyrosine specific protein phosphatases domain
UniProtKB:Q7SXZ4 592
UniProtKB:A8DZH6 592
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations