Gene

tbl1xr1b

ID
ZDB-GENE-040426-1192
Name
tbl1x receptor 1b
Symbol
tbl1xr1b Nomenclature History
Previous Names
  • tbl1xr1
  • zgc:63617
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have transcription corepressor activity. Predicted to be involved in histone deacetylation and regulation of transcription by RNA polymerase II. Predicted to localize to histone deacetylase complex. Is expressed in female organism. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 41. Orthologous to human TBL1XR1 (TBL1X receptor 1).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tbl1xr1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant non-syndromic intellectual disability 41 Alliance Mental retardation, autosomal dominant 41 616944
Pierpont syndrome 602342
Associated With tbl1xr1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR006594 LIS1 homology motif
Domain IPR017986 WD40-repeat-containing domain
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Repeat IPR020472 G-protein beta WD-40 repeat
Domain Details Per Protein
Protein Length G-protein beta WD-40 repeat LIS1 homology motif WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q6PGY0 362
UniProtKB:A5WVU0 510
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations