Gene
dand5
- ID
- ZDB-GENE-040421-2
- Name
- DAN domain family, member 5
- Symbol
- dand5 Nomenclature History
- Previous Names
-
- cha
- charon (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Acts upstream of or within several processes, including determination of left/right symmetry; formation of primary germ layer; and specification of animal organ axis polarity. Predicted to be located in extracellular region. Is expressed in Kupffer's vesicle; forerunner cell group; mesoderm; and tail bud. Orthologous to several human genes including CER1 (cerberus 1, DAN family BMP antagonist).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 51 figures from 43 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| visceral heterotaxy 13 | Alliance | Heterotaxy, visceral, 13, autosomal | 621079 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cerberus | Cystine knot, C-terminal | Cystine-knot cytokine | DAN |
|---|---|---|---|---|---|
|
UniProtKB:Q76C29
|
243 |
Interactions and Pathways
No data available
Plasmids