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ZIRC
ZFIN ID: ZDB-GENE-040219-4
Gene Name: toll-interleukin 1 receptor (TIR) domain containing adaptor protein
Gene Symbol: tirap
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: mal (1), MyD88 adapter-like protein (1)

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in malaria; primary immunodeficiency disease; and tuberculosis. Orthologous to human TIRAP (TIR domain  ...
GENE EXPRESSION
All Expression Data: 6 figures from 4 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa182 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tirap HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {Tuberculosis, protection against} 607948
    {Malaria, protection against} 611162
    {Bacteremia, protection against} 614382
    {Pneumococcal disease, invasive, protection against} 610799
    DISEASE ASSOCIATED WITH tirap VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    GO Terms (all 1)
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tirap No data available
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_002667112 (1)
    Genomic GenBank:CABZ01102203 (1) 7894bp
    Polypeptide UniProtKB:F1Q7L3 (1) 203aa
    Sequence Clusters UniGene:87438 (1)
    Sequence Information (all 12)
    OTHER tirap GENE PAGES
  • Alliance (1)
  • Gene:403148 (1)
  • Ensembl(GRCz11):ENSDARG00000074371 (2)
  • ORTHOLOGY for tirap (Chr: 18)
    CITATIONS (24)