Gene

tirap

ID
ZDB-GENE-040219-4
Name
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
Symbol
tirap Nomenclature History
Previous Names
  • mal (1)
  • MyD88 adapter-like protein (1)
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in malaria; primary immunodeficiency disease; and tuberculosis. Orthologous to human TIRAP (TIR domain containing adaptor protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tirap Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Bacteremia, protection against} 614382
{Malaria, protection against} 611162
{Tuberculosis, protection against} 607948
Associated With tirap Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
Family IPR017279 Toll-interleukin 1 receptor domain-containing adaptor protein, Tirap
Homologous_superfamily IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily
Domain Details Per Protein
Protein Length Toll-interleukin 1 receptor domain-containing adaptor protein, Tirap Toll/interleukin-1 receptor homology (TIR) domain Toll/interleukin-1 receptor homology (TIR) domain superfamily
UniProtKB:A0A8M6Z2S6 243
UniProtKB:A0A8M1REJ6 226
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations