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ZIRC
ZFIN ID: ZDB-GENE-040219-12
Gene Name: toll-like receptor 8b
Gene Symbol: tlr8b    Nomenclature History

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Previous Name: TIR8.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have DNA binding activity; RNA binding activity; and transmembrane signaling receptor activity. Predicted to be involved in several processes, including defense response to other organism; regulation of cytokine secretion; and toll-like receptor signaling pathway. Predicted to localize to the extracellular matrix and extracellular space. Is expressed in blood; heart; integument; and musculature system. Orthologous to human TLR8 (toll like receptor 8).
Genome Resources: Alliance (1),  Gene:403136 (1),  Ensembl(GRCz11):ENSDARG00000073675 (2)
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa45416 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tlr8b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tlr8b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process defense response to virus (more)
    Cellular Component integral component of membrane (more)
    Molecular Function DNA binding (more)
    GO Terms (all 16)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tlr8b-201 (1)    Ensembl 2406
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tlr8b No data available
    MARKER RELATIONSHIPS
    tlr8b Contained in: [BAC] DKEYP-33D3 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_017358120 (1)
    Genomic GenBank:CT583727 (1) 165752 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q9M5 (1) 1015 aa
    Sequence Clusters UniGene:161635 (1)
    Sequence Information (all 14)
    ORTHOLOGY for tlr8b ( Chr: 10 )
    CITATIONS (24)