Gene
fancd2
- ID
- ZDB-GENE-040116-5
- Name
- FA complementation group D2
- Symbol
- fancd2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have DNA polymerase binding activity. Involved in negative regulation of apoptotic process. Predicted to localize to condensed chromosome and nucleus. Human ortholog(s) of this gene implicated in Fanconi anemia; Fanconi anemia complementation group D2; and breast cancer. Is expressed in brain; eye; immature eye; and lens. Orthologous to human FANCD2 (FA complementation group D2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ramanagoudr-Bhojappa et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fanconi anemia complementation group D2 | Alliance | Fanconi anemia, complementation group D2 | 227646 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Armadillo-type fold | Fanconi anaemia protein FANCD2 |
|---|---|---|---|
|
UniProtKB:Q6WAS6
|
1445 | ||
|
UniProtKB:B3DJT4
|
1445 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fancd2-201
(1)
|
Ensembl | 4,762 nt | ||
| mRNA |
fancd2-202
(1)
|
Ensembl | 4,871 nt |
Interactions and Pathways
No data available
Plasmids
No data available