Gene

fancd2

ID
ZDB-GENE-040116-5
Name
FA complementation group D2
Symbol
fancd2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have DNA polymerase binding activity. Involved in negative regulation of apoptotic process. Predicted to localize to condensed chromosome and nucleus. Human ortholog(s) of this gene implicated in Fanconi anemia; Fanconi anemia complementation group D2; and breast cancer. Is expressed in brain; eye; immature eye; and lens. Orthologous to human FANCD2 (FA complementation group D2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Ramanagoudr-Bhojappa et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fancd2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Fanconi anemia, complementation group D2 227646
Associated With fancd2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR029448 Fanconi anaemia protein FANCD2
Homologous_superfamily IPR016024 Armadillo-type fold
Domain Details Per Protein
Protein Length Armadillo-type fold Fanconi anaemia protein FANCD2
UniProtKB:Q6WAS6 1445
UniProtKB:B3DJT4 1445
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA fancd2-201 (1) Havana 4762 nt
mRNA fancd2-202 (1) Ensembl 4871 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations