Gene
fancd2
- ID
- ZDB-GENE-040116-5
- Name
- FA complementation group D2
- Symbol
- fancd2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable DNA polymerase binding activity. Acts upstream of or within negative regulation of apoptotic process. Predicted to be active in condensed chromosome and nucleus. Is expressed in brain; eye; immature eye; and lens. Human ortholog(s) of this gene implicated in Fanconi anemia; Fanconi anemia complementation group D2; and breast cancer. Orthologous to human FANCD2 (FA complementation group D2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ramanagoudr-Bhojappa et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fanconi anemia complementation group D2 | Alliance | Fanconi anemia, complementation group D2 | 227646 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Armadillo-type fold | Fanconi anaemia protein FANCD2 |
|---|---|---|---|
|
UniProtKB:Q6WAS6
|
1445 | ||
|
UniProtKB:B3DJT4
|
1445 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fancd2-201
(1)
|
Ensembl | 4,762 nt | ||
| mRNA |
fancd2-202
(1)
|
Ensembl | 4,871 nt |
Interactions and Pathways
No data available
Plasmids
No data available