Gene
scap
- ID
- ZDB-GENE-040107-41
- Name
- SREBF chaperone
- Symbol
- scap Nomenclature History
- Previous Names
-
- si:dkey-201i6.4
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable sterol binding activity. Acts upstream of or within lipid metabolic process and lipid storage. Predicted to be located in ER to Golgi transport vesicle membrane and Golgi membrane. Predicted to be part of SREBP-SCAP complex. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human SCAP (SREBF chaperone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR000731 | Sterol-sensing domain |
| Domain | IPR053958 | HMGCR/SNAP/NPC1-like, sterol-sensing domain |
| Family | IPR030225 | Sterol regulatory element-binding protein cleavage-activating protein |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | HMGCR/SNAP/NPC1-like, sterol-sensing domain | Sterol regulatory element-binding protein cleavage-activating protein | Sterol-sensing domain | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B4M5
|
1294 | |||||||
|
UniProtKB:E9QEH6
|
1245 |
Interactions and Pathways
No data available
Plasmids
No data available