Gene
fa2h
- ID
- ZDB-GENE-031219-4
- Name
- fatty acid 2-hydroxylase
- Symbol
- fa2h Nomenclature History
- Previous Names
-
- cb1044 (1)
- zgc:153777
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable heme binding activity and metal ion binding activity. Is expressed in EVL; digestive system; ectoderm; peripheral olfactory organ; and pronephric duct. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 35. Orthologous to human FA2H (fatty acid 2-hydroxylase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1044 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 35 | Alliance | Spastic paraplegia 35, autosomal recessive | 612319 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome b5 | Cytochrome b5, heme-binding site | Cytochrome b5-like heme/steroid binding domain | Cytochrome b5-like heme/steroid binding domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q0P3V8
|
102 |
Interactions and Pathways
No data available
Plasmids
No data available