Gene
fut8a
- ID
- ZDB-GENE-031118-20
- Name
- fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
- Symbol
- fut8a Nomenclature History
- Previous Names
-
- fut8
- wu:fd47h04
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Enables alpha-(1->6)-fucosyltransferase activity. Acts upstream of or within N-glycan fucosylation; sarcomerogenesis; and skeletal muscle tissue development. Predicted to be located in Golgi cisterna membrane. Orthologous to human FUT8 (fucosyltransferase 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Dehnert et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Congenital disorder of glycosylation with defective fucosylation 1 | 618005 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR027350 | Glycosyltransferase family 23 (GT23) domain |
| Domain | IPR035653 | Alpha-(1,6)-fucosyltransferase, SH3 domain |
| Domain | IPR045573 | Alpha-(1,6)-fucosyltransferase, N- and catalytic domain |
| Family | IPR015827 | Alpha-(1,6)-fucosyltransferase |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha-(1,6)-fucosyltransferase | Alpha-(1,6)-fucosyltransferase, N- and catalytic domain | Alpha-(1,6)-fucosyltransferase, SH3 domain | Glycosyltransferase family 23 (GT23) domain | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1QW63 | InterPro | 581 |
Interactions and Pathways
No data available
Plasmids
No data available