Gene

fstb

ID
ZDB-GENE-031118-139
Name
follistatin b
Symbol
fstb Nomenclature History
Previous Names
  • fst2 (2)
  • fstl
  • hm:zeh1606
  • zeh1606
  • zgc:171342
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable activin binding activity. Predicted to be involved in cell differentiation; negative regulation of activin receptor signaling pathway; and regulation of BMP signaling pathway. Predicted to be active in extracellular space. Is expressed in several structures, including brain; heart; integument; pharyngeal arch 3-7 skeleton; and somite. Human ortholog(s) of this gene implicated in polycystic ovary syndrome. Orthologous to human FST (follistatin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fstb Human Ortholog
No data available
Associated With fstb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002350 Kazal domain
Domain IPR003645 Follistatin-like, N-terminal
Domain IPR015369 Follistatin/Osteonectin EGF domain
Domain IPR017878 TB domain
Homologous_superfamily IPR036058 Kazal domain superfamily
Homologous_superfamily IPR036773 TGF-beta binding (TB) domain superfamily
Domain Details Per Protein
Protein Length Follistatin-like, N-terminal Follistatin/Osteonectin EGF domain Kazal domain Kazal domain superfamily TB domain TGF-beta binding (TB) domain superfamily
UniProtKB:Q2PMI4 344
UniProtKB:A7MBP8 319
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations