ZFIN is now using GRCz12tu for Genomic Data
Gene
sypa
- ID
- ZDB-GENE-031104-2
- Name
- synaptophysin a
- Symbol
- sypa Nomenclature History
- Previous Names
-
- syp
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be located in membrane and synaptic vesicle. Predicted to be active in presynaptic active zone and synaptic vesicle membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 96. Orthologous to human SYP (synaptophysin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Hillman et al., 2025
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| non-syndromic X-linked intellectual disability 96 | Alliance | Intellectual developmental disorder, X-linked 96 | 300802 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Marvel domain | Synaptophysin/synaptoporin |
|---|---|---|---|---|
| UniProtKB:B0S5B9 | InterPro | 294 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers