Gene
g6pc1a.1
- ID
- ZDB-GENE-031001-4
- Name
- glucose-6-phosphatase catalytic subunit 1a, tandem duplicate 1
- Symbol
- g6pc1a.1 Nomenclature History
- Previous Names
-
- cb822 (1)
- g6pc
- g6pca.1
- g6pca
- zgc:92368
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have glucose-6-phosphatase activity. Predicted to be involved in gluconeogenesis and glucose 6-phosphate metabolic process. Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and type 2 diabetes mellitus. Is expressed in digestive system; liver; and yolk syncytial layer. Orthologous to human G6PC (glucose-6-phosphatase catalytic subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 27 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb822 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| glycogen storage disease Ia | Alliance | Glycogen storage disease Ia | 232200 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glucose-6-phosphatase | Phosphatidic acid phosphatase type 2/haloperoxidase | Phosphatidic acid phosphatase type 2/haloperoxidase superfamily |
|---|---|---|---|---|
|
UniProtKB:E7F5Z2
|
322 | |||
|
UniProtKB:A0A8M1N1J9
|
352 | |||
|
UniProtKB:A0A8M6Z3H1
|
203 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
g6pca.1-201
(1)
|
Ensembl | 1,266 nt | ||
| mRNA |
g6pca.1-202
(1)
|
Ensembl | 525 nt | ||
| mRNA |
g6pca.1-203
(1)
|
Ensembl | 1,298 nt |
Interactions and Pathways
No data available
Plasmids
No data available