Gene

erbb4b

ID
ZDB-GENE-030918-5
Name
erb-b2 receptor tyrosine kinase 4b
Symbol
erbb4b Nomenclature History
Previous Names
  • erbb4l
  • si:dkeyp-52f4.1
  • zmp:0000000963
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable ATP binding activity and transmembrane receptor protein tyrosine kinase activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in membrane. Is expressed in heart; muscle; nervous system; and trunk. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 19; colorectal cancer; esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Orthologous to human ERBB4 (erb-b2 receptor tyrosine kinase 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa12103Allele with one point mutationUnknownPremature StopENU
sa21550Allele with one point mutationUnknownSplice SiteENU
sa41494Allele with one point mutationUnknownSplice SiteENU
sa41495Allele with one point mutationUnknownPremature StopENU
sa41496Allele with one point mutationUnknownUnknownENU
sa45369Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With erbb4b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
amyotrophic lateral sclerosis type 19 Alliance Amyotrophic lateral sclerosis 19 615515
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Associated With erbb4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 9
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA erbb4b-202 (1) Ensembl 2,220 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEYP-52F4
Contained inFosmidCH1073-160H5ZFIN Curated Data
ContainsSTSzfish35937-102f03.p1c
    ZFIN Curated Data
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    Sequences
    Type Accession # Sequence Length (nt/aa) Analysis
    GenomicGenBank:CR762391 (1)177067 nt
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanERBB42
    Amino acid sequence comparison (2)
    Citations
    1 - 10 of 12
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