Gene
cntnap1
- ID
- ZDB-GENE-030916-2
- Name
- contactin associated protein 1
- Symbol
- cntnap1 Nomenclature History
- Previous Names
-
- caspr1
- si:ch211-250i3.4
- zmp:0000000749
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity. Predicted to be involved in paranodal junction assembly. Predicted to localize to integral component of membrane and paranode region of axon. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome and neuromuscular disease. Is expressed in posterior lateral line nerve. Orthologous to human CNTNAP1 (contactin associated protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000421 | Coagulation factor 5/8, C-terminal domain |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain |
| Domain | IPR003585 | Neurexin/syndecan/glycophorin C |
| Family | IPR050372 | Neurexin-related cell adhesion and synaptic protein |
| Homologous_superfamily | IPR008979 | Galactose-binding-like domain superfamily |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR036056 | Fibrinogen-like, C-terminal |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Length | Coagulation factor 5/8, C-terminal domain | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like calcium-binding domain | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | Fibrinogen-like, C-terminal | Galactose-binding-like domain superfamily | Laminin G domain | Neurexin-related cell adhesion and synaptic protein | Neurexin/syndecan/glycophorin C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8N7TDM7
|
1309 | |||||||||||
|
UniProtKB:X1WGG7
|
1309 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cntnap1-201
(1)
|
Ensembl | 3,894 nt | ||
| mRNA |
cntnap1-202
(1)
|
Ensembl | 4,033 nt | ||
| mRNA |
cntnap1-203
(1)
|
Ensembl | 2,166 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance