ZFIN is now using GRCz12tu for Genomic Data
Gene
cntnap1
- ID
- ZDB-GENE-030916-2
- Name
- contactin associated protein 1
- Symbol
- cntnap1 Nomenclature History
- Previous Names
-
- caspr1
- si:ch211-250i3.4
- zmp:0000000749
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium ion binding activity. Predicted to be involved in myelination; neuron projection morphogenesis; and signal transduction. Predicted to be located in basement membrane; membrane; and paranodal junction. Predicted to be active in plasma membrane and synapse. Is expressed in posterior lateral line nerve. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human CNTNAP1 (contactin associated protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000421 | Coagulation factor 5/8, C-terminal domain |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain |
| Domain | IPR003585 | Neurexin/syndecan/glycophorin C |
| Family | IPR050372 | Neurexin-related cell adhesion and synaptic protein |
| Homologous_superfamily | IPR008979 | Galactose-binding-like domain superfamily |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR036056 | Fibrinogen-like, C-terminal |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Additional Resources | Length | Coagulation factor 5/8, C-terminal domain | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like calcium-binding domain | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | Fibrinogen-like, C-terminal | Galactose-binding-like domain superfamily | Laminin G domain | Neurexin-related cell adhesion and synaptic protein | Neurexin/syndecan/glycophorin C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8N7TDM7 | InterPro | 1309 | |||||||||||
| UniProtKB:X1WGG7 | InterPro | 1309 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cntnap1-201
(1)
|
Ensembl | 3,894 nt | ||
| mRNA |
cntnap1-202
(1)
|
Ensembl | 4,033 nt | ||
| mRNA |
cntnap1-203
(1)
|
Ensembl | 2,166 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance