Gene

nid2a

ID
ZDB-GENE-030827-2
Name
nidogen 2a (osteonidogen)
Symbol
nid2a Nomenclature History
Previous Names
  • nid2
  • chunp382
  • fb77a09
  • fc18d04
  • im:7144424
  • wu:fb77a09
  • wu:fc18d04
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Involved in closure of optic fissure and fin regeneration. Predicted to localize to basement membrane and extracellular space. Is expressed in several structures, including axis; digestive system; nervous system; optic fissure; and pectoral fin bud. Orthologous to human NID2 (nidogen 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
18 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nid2a Human Ortholog
No data available
Associated With nid2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000716 Thyroglobulin type-1
Domain IPR000742 EGF-like domain
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR003886 NIDO domain
Domain IPR006605 G2 nidogen/fibulin G2F
Domain IPR024731 EGF domain
Domain IPR049883 NOTCH1 EGF-like calcium-binding domain
Family IPR051950 Developmental regulator and protease inhibitor
Homologous_superfamily IPR009017 Green fluorescent protein
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR011042 Six-bladed beta-propeller, TolB-like
Homologous_superfamily IPR036857 Thyroglobulin type-1 superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Repeat IPR000033 LDLR class B repeat
Domain Details Per Protein
Protein Length Developmental regulator and protease inhibitor EGF domain EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site G2 nidogen/fibulin G2F Green fluorescent protein Growth factor receptor cysteine-rich domain superfamily LDLR class B repeat NIDO domain NOTCH1 EGF-like calcium-binding domain Six-bladed beta-propeller, TolB-like Thyroglobulin type-1 Thyroglobulin type-1 superfamily
UniProtKB:A0A8M2BH70 1804
UniProtKB:A0A8M2BH21 1576
UniProtKB:A0A8M2BH48 1424
UniProtKB:A0A8M2BH51 1728
UniProtKB:A0A8M9PEL7 1728
UniProtKB:A0A8M2BHK2 1652
UniProtKB:A0A8M6YTZ1 1576
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations