Gene
sst6.1
- ID
- ZDB-GENE-030813-3
- Name
- somatostatin family member 6.1
- Symbol
- sst6.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor binding activity and neuropeptide hormone activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and regulation of cell migration. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in brain and ovary. Orthologous to human CORT (cortistatin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Somatostatin | Somatostatin/Cortistatin, C-terminal |
|---|---|---|---|---|
| UniProtKB:Q0P3Y2 | InterPro | 111 |
Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-237P19 | ||
| Encodes | cDNA | MGC:153708 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001045431 (1) | 699 nt | ||
| Genomic | GenBank:CR381533 (1) | 119891 nt | ||
| Polypeptide | UniProtKB:Q0P3Y2 (1) | 111 aa |
- Zebrafish Nomenclature Committee (2025) Nomenclature Data Curation (2025). Nomenclature Committee Submission.
- Zebrafish Nomenclature Committee (2024) Nomenclature Data Curation (2024). Nomenclature Committee Submission.
- Kappel, J.M., Förster, D., Slangewal, K., Shainer, I., Svara, F., Donovan, J.C., Sherman, S., Januszewski, M., Baier, H., Larsch, J. (2022) Visual recognition of social signals by a tectothalamic neural circuit. Nature. 608(7921):146-152
- Zhao, T., Ye, Z., Liu, Y., Lin, H., Li, S., Zhang, Y. (2022) Mutation of spexin2 promotes feeding, somatic growth, adiposity and insulin resistance in zebrafish. American journal of physiology. Regulatory, integrative and comparative physiology. 322(5):R454-R465
- Ahi, E.P., Tsakoumis, E., Brunel, M., Schmitz, M. (2021) Transcriptional study reveals a potential leptin-dependent gene regulatory network in zebrafish brain. Fish physiology and biochemistry. 47(4):1283-1298
- Szenker-Ravi, E., Ott, T., Khatoo, M., de Bellaing, A.M., Goh, W.X., Chong, Y.L., Beckers, A., Kannesan, D., Louvel, G., Anujan, P., Ravi, V., Bonnard, C., Moutton, S., Schoen, P., Fradin, M., Colin, E., Megarbane, A., Daou, L., Chehab, G., Di Filippo, S., Rooryck, C., Deleuze, J.F., Boland, A., Arribard, N., Eker, R., Tohari, S., Ng, A.Y., Rio, M., Lim, C.T., Eisenhaber, B., Eisenhaber, F., Venkatesh, B., Amiel, J., Crollius, H.R., Gordon, C.T., Gossler, A., Roy, S., Attie-Bitach, T., Blum, M., Bouvagnet, P., Reversade, B. (2021) Discovery of a genetic module essential for assigning left-right asymmetry in humans and ancestral vertebrates. Nature Genetics. 54(1):62-72
- Tang, W., Davidson, J.D., Zhang, G., Conen, K.E., Fang, J., Serluca, F., Li, J., Xiong, X., Coble, M., Tsai, T., Molind, G., Fawcett, C.H., Sanchez, E., Zhu, P., Couzin, I.D., Fishman, M.C. (2020) Genetic Control of Collective Behavior in Zebrafish. iScience. 23:100942
- Reuter, I., Jäckels, J., Kneitz, S., Kuper, J., Lesch, K.P., Lillesaar, C. (2019) Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish. Biology Open. 8(6):
- Tostivint, H., Gaillard, A.L., Mazan, S., Pézeron, G. (2019) Revisiting the evolution of the somatostatin family: Already five genes in the gnathostome ancestor. General and comparative endocrinology. 279:139147139-147
- Förster, D., Arnold-Ammer, I., Laurell, E., Barker, A.J., Fernandes, A.M., Finger-Baier, K., Filosa, A., Helmbrecht, T.O., Kölsch, Y., Kühn, E., Robles, E., Slanchev, K., Thiele, T.R., Baier, H., Kubo, F. (2017) Genetic targeting and anatomical registration of neuronal populations in the zebrafish brain with a new set of BAC transgenic tools. Scientific Reports. 7:5230
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