Gene

atad1a

ID

ZDB-GENE-030616-593

Name

ATPase family AAA domain containing 1a

Symbol

atad1a Nomenclature History

Previous Names

si:zc156n3.1
zgc:101570

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable ATP binding activity; ATP hydrolysis activity; and membrane protein dislocase activity. Predicted to be involved in extraction of mislocalized protein from mitochondrial outer membrane. Predicted to be located in peroxisomal membrane. Predicted to be active in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in hyperekplexia 4. Orthologous to human ATAD1 (ATPase family AAA domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:101570 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atad1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hyperekplexia 4	Alliance	Hyperekplexia 4	618011

Associated With atad1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003960	ATPase, AAA-type, conserved site
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR003959	ATPase, AAA-type, core
Domain	IPR041569	AAA ATPase, AAA+ lid domain
Family	IPR051701	Mitochondrial Outer Membrane Translocase MSP1 Subfamily
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	AAA ATPase, AAA+ lid domain	AAA+ ATPase domain	ATPase, AAA-type, conserved site	ATPase, AAA-type, core	Mitochondrial Outer Membrane Translocase MSP1 Subfamily	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q7ZZ25 InterPro	380
UniProtKB:B2GQN7 InterPro	380

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	atad1a-201 (1) Ensembl	Ensembl	1,487 nt	Select Tool ZFIN BLAST
mRNA	atad1a-203 (1) Ensembl	Ensembl	2,036 nt	Select Tool ZFIN BLAST
mRNA	atad1a-204 (1) Ensembl	Ensembl	2,475 nt	Select Tool ZFIN BLAST
mRNA	atad1a-205 (1) Ensembl	Ensembl	1,693 nt	Select Tool ZFIN BLAST
ncRNA	atad1a-002 (1) Ensembl	Ensembl	854 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations