Gene

auts2a

ID
ZDB-GENE-030616-571
Name
activator of transcription and developmental regulator AUTS2 a
Symbol
auts2a Nomenclature History
Previous Names
  • auts2
  • si:ch211-103d22.3
  • si:zc103d22.3
  • wu:fj83b10
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Involved in embryonic viscerocranium morphogenesis; forebrain neuron development; and neuron cellular homeostasis. Used to study microcephaly and syndromic intellectual disability. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 26. Is expressed in several structures, including anterior neural keel; anterior neural rod; brain; hindbrain neural keel; and posterior neural rod. Orthologous to human AUTS2 (activator of transcription and developmental regulator AUTS2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With auts2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant intellectual developmental disorder 26 Alliance Intellectual developmental disorder, autosomal dominant 26 615834
Associated With auts2a Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR023246 Autism susceptibility gene 2 protein
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations