Gene
adat3
- ID
- ZDB-GENE-030616-531
- Name
- adenosine deaminase tRNA specific 3
- Symbol
- adat3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable catalytic activity and metal ion binding activity. Predicted to contribute to tRNA-specific adenosine-34 deaminase activity. Predicted to act upstream of or within tRNA processing. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with brain abnormalities, poor growth, and dysmorphic facies. Orthologous to human ADAT3 (adenosine deaminase tRNA specific 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103555 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neurodevelopmental disorder with brain abnormalities, poor growth, and dysmorphic facies | Alliance | Neurodevelopmental disorder with brain abnormalities, poor growth, and dysmorphic facies | 615286 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytidine and deoxycytidylate deaminase domain | Cytidine deaminase-like |
|---|---|---|---|
|
UniProtKB:Q8JFW4
|
336 | ||
|
UniProtKB:Z4YHM2
|
336 |
Interactions and Pathways
No data available
Plasmids
No data available