Gene
triob
- ID
- ZDB-GENE-030616-399
- Name
- trio Rho guanine nucleotide exchange factor b
- Symbol
- triob Nomenclature History
- Previous Names
-
- trio
- si:dz230d15.1
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in axon guidance. Predicted to act upstream of or within central nervous system development and protein phosphorylation. Predicted to be active in cytoplasm. Predicted to be extrinsic component of membrane. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder and autosomal dominant intellectual developmental disorder 44. Orthologous to human TRIO (trio Rho guanine nucleotide exchange factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1114 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 44 | Alliance | Intellectual developmental disorder, autosomal dominant 44, with microcephaly | 617061 |
| Intellectual developmental disorder, autosomal dominant 63, with macrocephaly | 618825 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | ottdart00000001996 (1) | Havana | 2,271 nt |
Interactions and Pathways
No data available
Plasmids
No data available