ZFIN is now using GRCz12tu for Genomic Data
Gene
map4k2
- ID
- ZDB-GENE-030616-163
- Name
- mitogen-activated protein kinase kinase kinase kinase 2
- Symbol
- map4k2 Nomenclature History
- Previous Names
-
- map4k2l
- si:dz150l22.2
- si:dz263j20.1
- zgc:136670
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable MAP kinase kinase kinase kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Orthologous to human MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Nguyen et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001180 | Citron homology (CNH) domain |
| Family | IPR021160 | Mitogen-activated protein (MAP) kinase kinase kinase kinase |
| Family | IPR050629 | STE20/SPS1-related Proline-Alanine-rich Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Citron homology (CNH) domain | Mitogen-activated protein (MAP) kinase kinase kinase kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | STE20/SPS1-related Proline-Alanine-rich Kinase |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q1RLZ2 | InterPro | 865 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map4k2-201
(1)
|
Ensembl | 3,149 nt | ||
| mRNA |
map4k2-202
(1)
|
Ensembl | 704 nt | ||
| mRNA | ottdart00000004121 (1) | Havana | 2,945 nt | ||
| mRNA | ottdart00000004126 (1) | Havana | 3,107 nt | ||
| mRNA | ottdart00000004127 (1) | Havana | 2,408 nt | ||
| mRNA | ottdart00000004128 (1) | Havana | 1,517 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers